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This phenomenon, known as metabolic endotoxemia, has been linked to: Chronic inflammation Insulin resistance Obesity Metabolic syndrome In animal studies, even modest increases in circulating endotoxins have been shown to trigger inflammatory responses that interfere with metabolic regulation
doi: 10.1053/j.gastro.2016.01.032 48
Some individuals who previously enjoyed very hot foods may find them less appealing or more uncomfortable, especially during the dose-escalation phase
Clinical trials have shown that continued use produces ongoing weight loss and metabolic benefits over time
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